Selected Publications
*Co-corresponding authors

Harris SE, Hu Y, Bridges K, Cavazos FF Jr, Martyr JG, Guzman BB, Murn J, Aleman MM, Dominguez D. (2025) Dissecting RNA selectivity mediated by tandem RNA-binding domains. J Biol Chem. in press.

Franklin R, Zhang B, Fraier J, Chen M, Do BT, Padayao S, Wu K, Vander Heiden MG, Vakoc CR, Roe J, Ninova M, Murn J, Sykes DB, Cheloufi S. (2025) Histone Chaperones Coupled to DNA Replication and Transcription Control Divergent Chromatin Elements to Maintain Cell Fate. Genes Dev. in press.

Liu Y, He S, Pyo K, Zheng S, Chen M, Cheloufi S, Slavov N, Marzluff WF, Murn J. (2025) Composition and RNA binding specificity of metazoan RNase MRP. bioRxiv. Feb 23.
doi: https://doi.org/10.1101/2025.02.21.639568

Wei S, Dai X, Yuan J, He S, Shah K, Guo S, Duan Z, Murn J, Wang Y. (2025) Quantitative Proteomics Identifies Profilin-1 as a Pseudouridine-Binding Protein. J Am Chem Soc. Jan 15;147(2):1458- 1462. doi: 10.1021/jacs.4c17659. PMID: 39812085. 

Harris SE, Alexis MS, Giri G, Cavazos FF, Murn J, Aleman MM, Burge CB, Dominguez D. (2024) Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro.
Nat Commun. Sep 27;15(1):8400. doi: 10.1038/s41467-024-52231-7. PMID: 39333159

Larsen PB*, He S, Meyer TJ, Szurman-Zubrzycka M, Alfs C, Kwasniewska J, Pervis A, Gajecka M, Veerabahu A, Beaulieu TR, Bolaris SC, Eekhout T, De Veylder L, Abel S, Szarejko I, Murn J*. (2024) The stem cell niche transcription factor ETHYLENE RESPONSE FACTOR 115 participates in aluminum-induced terminal differentiation in Arabidopsis roots. Plant Cell Environ. Jul 15. doi: https://doi.org/10.1111/pce.15032

Shah K, He S, Turner DJ, Corbo J, Rebbani K, Dominguez D, Bateman JM, Cheloufi S, Igreja C, Valkov E*, Murn J*. (2024) Regulation by the RNA-binding protein Unkempt at its effector interface. Nat Commun. Apr 11;15:3159.

He S, Valkov E, Cheloufi1 S, Murn J. (2023) The nexus of RNA-binding proteins and their effectors. Nat Rev Genet. May;24(5):276-294.

Baskaran P, Mihaylov SR, Vinsland E, Shah K, Granat L, Ultanir SK, Tee AR, Murn J*, Bateman JM*. (2023) Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis. J Biol Chem. Jan:102788.

Franklin R, Guo Y, He S, Ji F, Chen M, Zhou X, Frankhouser D, Do BT, Chiem C, Jang M, Blanco A, Vander Heiden MG, Rockne RC, Ninova M, Sykes DB, Hochedlinger K, Lu R, Sadreyev R, Murn J*, Volk A*, Cheloufi S.* (2022) Regulation of chromatin accessibility by the Histone Chaperone CAF-1 sustains lineage fidelity. Nat Commun. Apr 29;13(1):2350.

Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM. (2021) The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. Aug;11(1):18299.

Shi J, Zhang Y, Tan D, Zhang X, Yan M, Zhang Y, Franklin R, Shahbazi M, Mackinlay K, Liu S, Kuhle B, James ER, Zhang L, Qu Y, Zhai Q, Zhao W, Zhao L, Zhou C, Gu W, Murn J, Guo J, Carrell DT, Wang Y, Chen X, Cairns BR, Yang W, Schimmel P, Zernicka-Goetz M, Cheloufi S, Zhang Y, Zhou T, Chen Q. (2021) PANDORA-seq expands the functional small RNA repertoire by overcoming RNA modifications. Nat Cell Biol. Apr;23(4):424-436.

Franklin R, Murn J*, Cheloufi S*. (2021) Cell Fate Decisions in the Wake of Histone H3 Deposition. Front Cell Dev Biol. Apr 20;9:654915.

Iyer EPR, Punthambaker S, Liu S, Jindal K, Farrell M, Murn J, Ferrante T, Rudnicki S, Kohman RE, Wassie AT, Goodwin D, Chen F, Alon S, Sinha A, Milanova D, Aron L, Camplisson C, Skrynnyk A, Reginato PL, Conway N, Aach J, Yankner B, Boyden ES, Church GM. (2018) Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses. bioRxiv. Mar 20.

Murn J*, Shi Y*. (2017) The winding path of protein methylation research: milestones and new frontiers. Nat Rev Mol Cell Biol. Aug;18(8):517-527.

Murn J, Teplova M, Zarnack K, Patel DJ, Shi Y. (2016) Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt. Nat Struct Mol Biol. Jan;23(1):16-23.

Cheloufi S, Elling U, Hopfgartner B, Jung Y, Murn J, Badeaux A, Blanco A, Ang CE, Tennen D, Ferrari F, Wesche D, Abazova N, Hogue M, Tasdemir N, Rathert P, Vidal S, Fellner M, Wenzel D, Zinner M, Stadtfeld M, Almouzni G, Lowe SW, Rinn J, Wernig M, Shi Y, Park P, Penninger JM, Zuber J, Hochedlinger K. (2015) The histone chaperone CAF-1 safeguards somatic cell identity. Nature. Dec 10; 528(7581): 218-24.

Murn J*, Zarnack K, Yang YJ, Durak O, Murphy EA, Cheloufi S, Gonzalez DM, Teplova M, Curk T, Zuber J, Patel DJ, Ule J, Luscombe NM, Tsai LH, Walsh CA, Shi Y*. (2015) Control of a neuronal morphology program by an RNA-binding zinc finger protein Unkempt. Genes Dev. Mar 1;29(5):501-12.

Laurent B, Ruiti L, Murn J, Hempel K, Ferrao R, Xiang Y, Liu S, Garcia BA, Wu H, Wu F, Steen H, Shi Y. (2015) The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation. Mol Cell. Mar 19;57(6):957-70.

Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM. Rapid neurogenesis through transcriptional activation in human stem cells. Mol Syst Biol. Nov 17;10:760.

Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco A, Chen S, Stützer A, Armache KJ, Simon MD, Xu C, Ali M, Murn J, Prisic S, Kutateladze TG, Vakoc CR, Min J, Kingston RE, Fischle W, Warren ST, Page DC, Shi Y. (2014) A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response. Cell. May 8;157(4):869-81.

Yang YJ, Baltus AE, Mathew RS, Murphy EA, Evrony GD, Gonzalez DM, Wang EP, Marshall-Walker CA, Barry BJ, Murn J, Tatarakis A, Mahajan MA, Samuels HH, Shi Y, Golden JA, Mahajnah M, Shenhav R, Walsh CA. (2012) Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation. Cell. Nov 21;151(5):1097-112.

Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LC. (2011) Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell. Aug 16;20(2):173-86.

Murn, J, Mlinaric-Rascan, I, Vaigot, P, Frouin, V, Gidrol, X. (2009) A Myc-regulated transcriptional network controls B-cell fate in response to BCR triggering. BMC Genomics. Jul 17;10:323.

Murn, J, Tendil, S, Wu, N, Alibert, O, Gidrol, X. Prostaglandin E2 regulates B-cell proliferation through a candidate tumor suppressor, Ptger4. (2008) J Exp Med. Dec 22;205(13):3091-103.

Murn, J, Urleb, U & Mlinaric-Rascan, I. (2004) Internucleosomal DNA cleavage in apoptotic WEHI 231 cells is mediated by a chymotrypsin-like protease. Genes Cells 9. Nov;9(11):1103-11.